CD86 is officially called Cluster of Differentiation 86, also known as B7-2.
Being a member of the immunoglobulin superfamily, it is a protein expressed on antigen-presenting cells.
The CD86 gene is mapped to human chromosome 3q21.
The smallest transcript, 828 bp, which the authors termed CD86deltaTM, has a deletion from nucleotide 686 to nucleotide 829 (i.e., exon 6) and encodes a 275-amino acid protein.
CD86deltaTM enhances proliferation and cytokine production by both naive and memory T cells, providing costimulatory signals necessary for T cell activation and survival.
UniProt Number:P42082
Gene ID:CD86
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes mouse CD86. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Mo
Immunogen：A synthetic peptide corresponding to a sequence at the N-terminal of mouse CD86, different from the related rat sequence by 2 amino acids
