Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes.
CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins.
Caveolin-1 and caveolin-2 are expressed in neuronal cells.
Caveolin-2 was upregulated in response to neuronal cell injury.
The CAV2 gene is mapped to 7q31.1-q31.2 .The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons.
The boundary of the last exon of CAV1 and CAV2 are analogous, suggesting that they arose through gene duplication.
The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.
UniProt Number:P51636
Gene ID:CAV2
Applications:Suitable for use in Western Blot and Immunohistochemistry (Paraffin).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human, mouse and rat CAV2. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to a sequence at the N-terminal of human CAV2, different from the related rat and mouse sequence by one amino acid.
