84-2092-80 Annexin A2 (Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV) 100ug 144163
84-2092-80 Annexin A2 (Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV) 100ug 144163
Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene.
The ANXA2 gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively.
Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
This protein is a member of the annexin family.
Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways.
This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption.
Richard et al.
(1994) presented an integration of the physical, expression, and genetic maps of human chromosome 15.
They placed the ANXA2 gene in their region IV, i.e., 15q21-q22, thus confirming the previous localization.
UniProt Number:P07355
Gene ID:ANXA2
Applications:Suitable for use in Western Blot, Immunohistochemistry (Paraffin and Frozen).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity:Recognizes human, mouse and rat Annexin A2. No crossreactivity with other proteins.
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:A synthetic peptide corresponding to a sequence in the middle region of human Annexin A2, different from the rat sequence by one amino acid.