AIMP2, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2, also known as AIMP2, is an enzyme that in humans is encoded by the AIMP2 gene.
AIMP2 encodes a predicted 312-amino acid protein.
The AIMP2 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2.
AIMP2 and HRI overlap slightly and are arranged in a tail-to-tail fashion.
AIMP2 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head.
AIMP2 is transcribed in the opposite direction compared to HRI and PMS2.
AIMP2 is a scaffold required for the assembly and stability of the multi-tRNA synthetase complex.
AIMP2 can work as a mediator of TGF-beta signaling and its functional importance in the control of MYC during lung differentiation.
UniProt Number:Q13155
Gene ID:AIMP2
Applications:Suitable for use in Western Blot and Immunohistochemistry (Paraffin).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human, mouse and rat AIMP2. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to a sequence in the middle region of human AIMP2, different from the related rat and mouse sequences by three amino acids.
