84-2092-52 ACE (ACE1, CD143, DCP, DCP1, peptidyl-dipeptidase A, Kininase II, Dipeptidyl carboxypeptidase I, Angiotensin-converting enzyme, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1) 100ug 144116
84-2092-52 ACE (ACE1, CD143, DCP, DCP1, peptidyl-dipeptidase A, Kininase II, Dipeptidyl carboxypeptidase I, Angiotensin-converting enzyme, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1) 100ug 144116
Angiotensin I converting enzyme (ACE), also called DCP or CD143 is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is thought to play a critical role in blood pressure regulation.
This gene is mapped to 17q23.3.
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II.
Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance.
This enzyme plays a key role in the renin-angiotensin system.
Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies.
UniProt Number:P12821
Gene ID:ACE
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity:Recognizes human and mouse ACE. No crossreactivity with other proteins.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo
Immunogen:A synthetic peptide corresponding to a sequence at the N-terminus of human ACE, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.