84-2092-51　ACE (ACE1, CD143, DCP, DCP1, peptidyl-dipeptidase A, Kininase II, Dipeptidyl carboxypeptidase I, Angiotensin-converting enzyme, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1) 100ug　144115

特徴

• Angiotensin I converting enzyme (ACE), also called DCP or CD143, is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is thought to play a critical role in blood pressure regulation.
• ACE gene is mapped to 17q23.3.
• This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II.
• Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance.
• This enzyme plays a key role in the renin-angiotensin system.
• Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies.
• UniProt Number:P12821
• Gene ID:ACE
• Applications:Suitable for use in Western Blot and Immunohistochemistry (Paraffin).
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Handling:Store at -20˚C for one year.
• After reconstitution, store at 4˚C for one month.
• Can also be aliquoted and stored frozen at -20˚C for long term
• Avoid repeated freezing and thawing.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.