84-2024-21　［取扱停止］HDAC3, CT (HDAC3, Histone deacetylase 3, RPD3-2, SMAP45) (PE) 200ul　036478-PE

特徴

• Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
• Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
• The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family.
• It has histone deacetylase activity and represses transcription when tethered to a promoter.
• It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.
• This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis.
• This gene is regarded as a potential tumor suppressor gene.
• [provided by RefSeq].
• Applications:Suitable for use in Western Blot, Immunohistochemistry, FLISA
• Recommended Dilution:FLISA: 1:1,000Western Blot: 1:100-500Immunohistochemistry: 1:10-50
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: PE conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.