Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types.
Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells.
Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily.
These desmoglein gene family members are located in a cluster on chromosome 18.
This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Applications:Suitable for use in Western Blot and FLISA.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS. No preservative added. Labeled with R-Phycoerythrin (PE).
Specificity：Recognizes human DSG3.
Isotype：IgG
Calc Applications Abbrev：FLISA WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 8-36 in the N-terminal region of human DSG3, UniProt Accession #NP_001935.2; P32926.
