84-2010-47　DSG2, CT (DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC) (PE) 200ul　034828-PE

特徴

• Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types.
• This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells.
• Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily.
• These desmoglein gene family members are located in a cluster on chromosome 18.
• This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
• Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
• Applications:Suitable for use in Western Blot, Immunohistochemistry and FLISA.
• Other applications have not been tested.
• Recommended Dilutions:Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: PE conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.