CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation.
Studies in mice have demonstrated that DNA methylation is required for mammalian development.
TRDMT1 shows similarity to DNA methyltransferases, but this protein does not display methyltransferase activity.
The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.
Applications:Suitable for use in Immunohistochemistry, FLISA
Recommended Dilution:FLISA: 1:1,000Western Blot: Not testedImmunohistochemistry: 1:50Immunoprecipitation Not tested Flow cytometry Not tested
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：FLISA IHC
Calc Crossreactivity：Hu
Immunogen：DNMT2 (TRDMT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190~220 amino acids from the Center region of human DNMT2.
