The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E.
coli RNAse III.
Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs.
Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing.
Applications:Suitable for use in FLISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:c.elegans
Grade:Affinity Purified
Purity:Purified by Protein A/G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Specificity:Recognizes c. elegans Dcr-1.
Isotype:IgG
Calc Applications Abbrev:FLISA
Calc Crossreactivity:Ce
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1068-1097 of C. elegans Dcr-1.