84-2000-25　［取扱停止］CDC25A, phosphorylated (Thr506) (M-phase Inducer Phosphatase 1, Dual Specificity Phosphatase Cdc25A) (PE) 200ul　C2560-01R-PE

特徴

• CDC25A is a member of the CDC25 family of phosphatases.
• CDC25A is required for progression from G1 to the S phase of the cell cycle.
• It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups.
• CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division.
• CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
• Two transcript variants encoding different isoforms have been found for this gene.
• Applications:Suitable for use in FLISA, Western Blot, and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:FLISA: 1:1,000Western Blot: 1:100-1:500Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: PE conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.