84-1986-07　［取扱停止］Abl1, ID (Abl1, Abl, Tyrosine-protein kinase ABL1, Abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Proto-oncogene c-Abl, p150) (PE) 200ul　031503-PE

特徴

• Protein kinase that regulates key processes linked to cell growth and survival.
• Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion.
• Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.
• Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired.
• Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
• Applications:Suitable for use in Western Blot, Immunohistochemistry, ELISA
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-500Immunohistochemistry: 1:10-50
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: PE conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.