84-1980-71 [取扱停止]WDR48, CT (WDR48, KIAA1449, UAF1, WD repeat-containing protein 48, USP1-associated factor 1, WD repeat endosomal protein, p80) (Azide free) (HRP) 200ul 043838-HRP

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冷凍

特徴

  • Regulator of deubiquitinating complexes.
  • Acts as a strong activator of USP1 by enhancing the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself.
  • Also activates deubiquitinating activity of complexes containing USP12 and USP46, respectively.
  • Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate.
  • In case of infection by Herpes virus saimiri, may play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes.
  • Induces lysosomal vesicle formation via interaction with Herpes virus saimiri tyrosine kinase-interacting protein (TIP).
  • Subsequently, TIP recruits tyrosine-protein kinase LCK, resulting in down-regulation of T-cell antigen receptor TCR.
  • May play a role in generation of enlarged endosomal vesicles via interaction with TIP.
  • In case of infection by papillomavirus HPV11, promotes the maintenance of the viral genome via its interaction with HPV11 helicase E1.
  • Applications:Suitable for use in Western Blot, Immunohistochemistry ELISA
  • Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-500Immunohistochemistry: 1:50-100
  • Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
  • For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
  • Aliquots are stable at -20°C for 12 months after receipt.
  • Dilute required amount only prior to immediate use.
  • Further dilutions can be made in assay buffer.
  • Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
  • For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Note: Applications are based on unconjugated antibody.

仕様

  • Size:200ul
  • Host:rabbit
  • Source Antibody:human
  • Grade:Affinity Purified
  • Purity:Purified by Protein A affinity chromatography.
  • Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
  • Specificity:Human
  • Isotype:IgG
  • Calc Applications Abbrev:E IHC WB
  • Calc Crossreactivity:Hu
  • Immunogen:WDR48 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 610-638 amino acids from the C-terminal region of human WDR48.
  • Shelf Life:6months
  • Swiss Prot Number:Q8TAF3
  • EU Commodity Code:30021010
  • この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
  • 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
  • 【試薬に関するお問合せ】
  • アズワン株式会社 試薬・プロセス材料グループ
  • TEL:06-6447-8641
  • FAX:06-6447-8642
  • E-mail:[email protected]
アズワン品番
84-1980-71
型番
043838-HRP
入り数
1個
標準価格
226,000円(税抜)
WEB価格
取扱停止
アズワン在庫 [?]
数量

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