TM173 acts as a facilitator of innate immune signaling.
Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression.
May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.
May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II).
Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Applications:Suitable for use in Western Blot, Immunohistochemistry
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：TM173 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318~348 amino acids from the C-terminal region of human TM173.
