84-1944-39 [取扱停止]PAK1, phosphorylated (Thr423) (Serine/Threonine-protein Kinase PAK 1, p21-activated Kinase 1, PAK-1, p65-PAK, Alpha-PAK) (Azide free) (HRP) 200ul P2488-01P-HRP
特徴
- PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling.
- PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4.
- These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities.
- PAK1 regulates cell motility and morphology.
- Applications:Suitable for use in ELISA and Dot Blot.
- Other applications not tested.
- Recommended Dilution:ELISA: 1:1,000 Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
- Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
- For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
- Aliquots are stable at -20°C for 12 months after receipt.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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- Note: Applications are based on unconjugated antibody.
仕様
- Size:200ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
- Specificity:Recognizes human PAK1 when phosphorylated at Thr423.
- Isotype:IgG
- Calc Applications Abbrev:DB E
- Calc Crossreactivity:Hu
- Immunogen:Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr423 of human PAK1 (KLH).
- Shelf Life:6months
- Swiss Prot Number:Q13153
- EU Commodity Code:30021010
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