MLKLAK is a member of the MAPKKK family of signal transduction molecules.
It possesses an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM).
This magnesium-binding protein forms homodimers and is located in the cytoplasm.
The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells.
The protein also has pro-apoptotic activity.
Applications:Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-1:500Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Specificity:Recognizes human MLKLAK.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide selected from the center region of human MLKLAK (KLH).
Shelf Life:6months
Swiss Prot Number:Q9NYL2-2
EU Commodity Code:30021010
商品名:MLKLAK (MLK-like Mitogen-activated Protein Triple Kinase, MLTK, AZK, Human Cervical Cancer Suppressor Gene 4 Protein, HCCS4, HCCS-4, Leucine Zipper- and Sterile alpha Motif-containing Kinase, Mitogen-activated Protein Kinase Kinase Kinase MLT, Mixed Lineage Kinase-related Kinase, MLK-related Kinase, MRK, MLK7, Sterile alpha Motif- and Leucine Zipper-containing Kinase AZK, ZAK) (Azide free) (HRP) 200ul