84-1933-99　［取扱停止］MITF, NT (MITF, BHLHE32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32) (Azide free) (HRP) 200ul　038445-HRP

特徴

• This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features.
• It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes.
• Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.
• Alternatively spliced transcript variants encoding different isoforms have been identified.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications have not been tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.