LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors.
It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
Applications:Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Specificity：Recognizes human LRRN6A.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 62-92 in the N-terminal region of human LRRN6A, UniProt Accession #Q96FE5.Species Sequence Homology: chicken, monkey and mouse
Shelf Life：1year
Swiss Prot Number：Q96FE5
EU Commodity Code：30021010
商品名：Leucine Rich Repeat and Ig Domain Containing 1, NT (Leucine-rich Repeat and Immunoglobulin-like Domain-containing Nogo Receptor-interacting Protein 1, Lingo 1, LINGO1, Lingo-1, FLJ14594, Leucine-rich Repeat and Immunoglobilin Domain-containing Protein 1, Leucine-rich Repeat Neuronal Protein 1, LERN1, Leucine-rich Repeat Neuronal Protein 6A, LRRN6A, MGC17422, UNQ201/PRO227) (Azide free) (HRP) 200ul
