84-1897-93　［取扱停止］COQ3, ID (Dihydroxyhexaprenylbenzoate Methyltransferase, 3,4-dihydroxy-5-hexaprenylbenzoate Methyltransferase, Hexaprenyldihydroxybenzoate Methyltransferase, Mitochondrial, DHHB Methyltransferasem, DHHB-MTase, DHHB-MT, COQ3, UG0215E05) (Azide free) (HRP) 200ul　C7900-65-HRP

特徴

• Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]).
• This lipid consists of a hydrophobic isoprenoid tail and a quinone head group.
• The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane.
• The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain.
• COQ3 is an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q.
• This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q.
• The COQ3 is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-1:500Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.