CDH4 is a classical cadherin from the cadherin superfamily.
It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.
Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth.
In addition, a role in kidney and muscle development is indicated.
Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines.
Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
Applications:Suitable for use in Western Blot, Immunohistochemistry, ELISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by peptide immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：CDH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182~211 amino acids from the N-terminal region of human CDH4.
