84-1872-33 [取扱停止]MAPRE1, NT (MAPRE1, Microtubule-associated protein RP/EB family member 1, APC-binding protein EB1, End-binding protein 1) (FITC) 200ul 038190-FITC
84-1872-33 [取扱停止]MAPRE1, NT (MAPRE1, Microtubule-associated protein RP/EB family member 1, APC-binding protein EB1, End-binding protein 1) (FITC) 200ul 038190-FITC
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer.
This protein localizes to microtubules, especially the growing ends, in interphase cells.
During mitosis, the protein is associated with the centrosomes and spindle microtubules.
The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein.
Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability.
This gene is a member of the RP/EB family.
Applications:Suitable for use in Western Blot, Immunohistochemistry and FLISA.
Other potential application, though not tested is Direct Flow Cytometry.
Other applications have not been tested.
Recommended Dilution:Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Recognizes human MAPRE1. Species crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:FLISA IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 44-71 in the N-terminal region of human MAPRE1. Species sequence homology: bovine, chicken, rat, xenopus