84-1872-20　［取扱停止］Glypican 3 (GPC3), CT (GPC3, OCI5, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Secreted glypican-3) (FITC) 200ul　036110-FITC

特徴

• GPC3 is a cell surface proteoglycan that bears heparan sulfate.
• This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
• Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage.
• These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition.
• Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS).
• SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
• Applications:Suitable for use in Western Blot, FLISA
• Recommended Dilution:FLISA: 1:1,000Western Blot: 1:50-100
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.