LINGO-1 (LRR and Ig domain-containing Nogo Receptor interating protein) is a nervous system-specific LRR-Ig-containing protein with an important role in CNS biology.
LINGO-1 was discovered in a sequence database search for human SLIT homologs that were selectively expressed in the brain.
LINGO-1 is a transmembrane protein that is a component of the Nogo-66 receptor complex.
It binds NgR1 and p75 and is an additional functional componenet of the NgR1/p75 signaling complex.
Applications:Suitable for use in Dot Blot, FLISA
Recommended Dilution:FLISA: 1:1,000Dot blot 1:500
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Human
Isotype:IgG
Calc Applications Abbrev:DB FLISA
Calc Crossreactivity:Hu
Immunogen:Phospho-LINGO-1(LRRN6A)-pS596 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 582~611 amino acids surrounding pS596 of human LINGO-1(LRRN6A).