Ptf1a is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development.
The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates.
This protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase.
Mutations in the Ptf1a gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.
Applications:Suitable for use in Western Blot, Immunohistochemistry, FLISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Human
Isotype:IgG
Calc Applications Abbrev:FLISA IHC WB
Calc Crossreactivity:Hu
Immunogen:Ptf1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Ptf1a.