The protein encoded by this gene belongs to the integrin alpha chain family.
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis.
This protein functions as a receptor for the basement membrane protein laminin-1.
It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis.
Defects in this gene are associated with congenital myopathy.
Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Recognizes human ITGA7.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 229-257 in the N-terminal region of human ITGA7, UniProt Accession #Q13683.Species sequence homology: mouse