BSDC1 is a 430 amino acid protein encoded by a gene mapping to chromosome 1.
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome.
There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A.
When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs.
The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration.
The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis.
Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia.
Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Applications:Suitable for use in Western Blot, FLISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：FLISA WB
Calc Crossreactivity：Hu
Immunogen：BSDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-425 amino acids from the C-terminal region of human BSDC1.
