The protein encoded by this gene is a member of the family of voltage-gated chloride channels.
Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport.
This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption.
Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3).
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
[provided by RefSeq].
Applications:Suitable for use in Western Blot, FLISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Mouse
Isotype:IgG
Calc Applications Abbrev:FLISA WB
Calc Crossreactivity:Mo
Immunogen:CLCNKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-40 amino acids from the N-terminal region of human CLCNKB.