84-1827-41　［取扱停止］SSRP1, CT (SSRP1, FACT80, FACT complex subunit SSRP1, Chromatin-specific transcription elongation factor 80kD subunit, Facilitates chromatin transcription complex 80kD subunit, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, T160) (FITC) 200ul　042332-FITC

特徴

• The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT.
• FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation.
• FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin.
• This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA.
• This protein also functions as a co-activator of the transcriptional activator p63.
• An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
• Applications:Suitable for use in Western Blot, FLISA
• Recommended Dilution:FLISA: 1:1,000Western Blot: 1:100-500
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.