Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway.
May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity.
Interacts with the SH2 domain of Grb2.
May phosphorylate the voltage-gated potassium channel protein Kv1.2.
Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.
Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation (By similarity).
Applications:Suitable for use in Western Blot, Immunohistochemistry, FLISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Specificity：Human, mouse
Isotype：IgG
Calc Applications Abbrev：FLISA IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Mouse Ptk2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-701 amino acids from the Central region of Mouse Ptk2b.
