84-1802-48 MITF, NT (MITF, BHLHE32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32) (FITC) 200ul 038445-FITC
84-1802-48 MITF, NT (MITF, BHLHE32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32) (FITC) 200ul 038445-FITC
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features.
It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes.
Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.
Alternatively spliced transcript variants encoding different isoforms have been identified.
Applications:Suitable for use in Western Blot, Immunofluorescence, Flow Cytometry (Not Tested) and FLISA.
Other applications have not been tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Recognizes human MITF.
Isotype:IgG
Calc Applications Abbrev:FLISA IF WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-28 in the N-terminal region of human MITF. Species Sequence Homology: mouse