84-1786-21　［取扱停止］MAGEL2, CT (MAGE-like Protein 2, Necdin-like Protein 1, Protein nM15, NDNL1) (FITC) 200ul　M1750-15-FITC

特徴

• Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta.
• These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types.
• Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy.
• Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes.
• Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
• Applications:Suitable for use in FLISA and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:FLISA: 1:1,000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.