84-1775-55　［取扱停止］ASCL1, CT (Class A Basic Helix-loop-helix Protein 46, Achaete-scute Homolog 1, ASH-1, hASH1, bHLHa46, ASH1, BHLHA46, HASH1) (FITC) 200ul　A3619-80B-FITC

特徴

• ACSL1, alternatively titled Hash1 or Mash1, is a member of the basic helix-loop-helix (BHLH) family of transcription factors.
• It activates transcription by binding to the E box (5'-CANNTG-3').
• Dimerization with other BHLH proteins is required for efficient DNA binding.
• ACSL1 plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons.
• The protein is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers.
• The presence of a CAG repeat in the gene suggests it may also play a role in tumor formation.
• Applications:Suitable for use in FLISA, Western Blot, and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:FLISA: 1:1,000Western Blot: 1:100-1:500Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.