84-1763-03　［取扱停止］GLP1, ID (ZGLP1, GLP1, GATA-type zinc finger protein 1, GATA-like protein 1) (Biotin) 200ul　036087-Biotin

特徴

• Glucagon is initially synthesised as proglucagon, which is 180 amino acids in length and is cleaved proteolytically.
• It contains a region corresponding to Glucagon itself, in addition to a signal peptide, spacer regions and two Glucagon-like peptide sequences.
• GLP1 is encoded by the fourth exon of the six in the human Glucagon gene.
• It is 37 amino acids in length and has 48% amino acid sequence homology to Glucagon, and is thought to have arisen by gene duplication.
• The sequence of GLP1 is conserved across many species, however, indicating that it has a particular function.
• GLP1 is a potent insulin secretagogue, renders pancreatic beta cells 'glucose-competent' and may be useful in the treatment of diabetes mellitus.
• Applications:Suitable for use in Western Blot, Flow Cytometry (Not Tested), ELISA
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-500
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.