Transcriptional regulator that acts as a repressor or an activator.
Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence).
Binds to element F in an E-box sequence-specific manner.
Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity).
Collaborates with MITF in target gene activation (By similarity).
Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity).
Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity).
Binds DNA in a homo-or heterodimeric form.
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC.
