The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus.
The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction.
This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm.
Three transcript variants encoding the same protein have been found for this gene.
[provided by RefSeq].
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：GEMIN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-239 amino acids from the C-terminal region of human GEMIN8.
