84-1734-01　CD68, ID (DKFZp686M18236, GP110, Macrophage Antigen CD68, Macrosialin, Scavenger Receptor Class D Member 1, SCARD1) (Biotin) 200ul　033530-Biotin

特徴

• This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages.
• It is a member of the lysosomal/ endosomal-associated membrane glycoprotein (LAMP) family.
• The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface.
• It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins.
• The protein is also a member of the scavenger receptor family.
• Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages.
• Alternative splicing results in multiple transcripts encoding different isoforms.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.