84-1725-28　［取扱停止］MDS1, ID (MECOM, MDS1, MDS1 and EVI1 complex locus protein MDS1, Myelodysplasia syndrome 1 protein, Myelodysplasia syndrome-associated protein 1) (Biotin) 200ul　038304-Biotin

特徴

• MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped.
• MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1.
• MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame.
• In cells with translocation t (3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1.
• EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
• Applications:Suitable for use in Western Blot, ELISA
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-500
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.