Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain.
It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane.
The complex consists of 13 mitochondrial- and nuclear-encoded subunits.
The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities.
The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.
This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme.
A pseudogene COX5AP1 has been found in chromosome 14q22.
[provided by RefSeq].
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Specificity:Mouse
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Mo
Immunogen:COX5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human COX5A.