84-1689-22　BHLHA15, CT (BHLHA15, BHLHB8, MIST1, Class A basic helix-loop-helix protein 15, Class B basic helix-loop-helix protein 8, Muscle, intestine and stomach expression 1) (Biotin) 200ul　032507-Biotin

特徴

• Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated.
• Repression may occur through muscle-specific E-box occupancy by homodimers.
• May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain.
• Serves as a key regulator of acinar cell function, stability, and identity.
• Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport.
• May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages.
• Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity).
• Applications:Suitable for use in Flow Cytometry (Not Tested), ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.