84-1684-71　［取扱停止］TP53INP2, CT (Tumor Protein p53-inducible Nuclear Protein 2, p53-inducible Protein U, PIG-U, PINH, C20orf110, DOR) (Biotin) 200ul　T5501-20-Biotin

特徴

• TP53INP2/DOR is a scaffold protein that recruits LC3 and/or LC3-related proteins to the autophagosome membrane by interacting with the transmembrane protein VMP1.
• TP53INP2 translocates from the nucleus to the autophagosome structures after activation of autophagy by rapamycin or starvation.
• TP53INP2 is necessary for autophagosome development because its small interfering RNA-mediated knockdown strongly decreases sensitivity of mammalian cells to autophagy.
• Applications:Suitable for use in ELISA, Flow Cytometry (Not Tested), Immunohistochemistry and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1,000Flow Cytometry (Not Tested): 1:10-1:50Immunohistochemistry: 1:50-1:100Western Blot: 1:100-1:500Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.