84-1683-76　［取扱停止］RUNX2, phosphorylated (Ser465) (Runt-related Transcription Factor 2, Core-binding Factor Subunit alpha-1, CBF-alpha-1, Acute Myeloid Leukemia 3 Protein, Oncogene AML-3, Polyomavirus Enhancer-binding Protein 2 alpha A Subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 Enhancer Factor 1 alpha A Subunit, SL3/AKV Core-binding Factor alpha A Subunit, Osteoblast-specific Transcription Factor 2, OSF-2, AML3 ...　R9915-10B-Biotin

特徴

• Runx2 is a member of the RUNX family of transcription factors.
• It is a nuclear protein with an Runt DNA-binding domain.
• This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression.
• It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex.
• Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
• Applications:Suitable for use in ELISA and Dot Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1,000 Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.