84-1679-76　［取扱停止］MARK4, NT (MAP/microtubule Affinity-regulating Kinase 4, KIAA1860, MAP/microtubule Affinity-regulating Kinase-like 1, MARKL1, MARKL1L, MARK4L, MARK4S) (Biotin) 200ul　M2408-01N-Biotin

特徴

• MARK4 contains an N-terminal serine/threonine kinase domain, a central ubiquitin-associated domain, and a C-terminal KA1-associated kinase domain.
• RT-PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.
• Northern blot analysis reveals ubiquitous expression of a 3.6-kb transcript, with highest expression in testis.
• Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression.
• Colony-forming assays show that MARK4 antisense reduces the growth of SNU475 cells.
• It has been suggested that MARK4 provides a growth advantage to cells.
• Applications:Suitable for use in ELISA and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1,000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.