COMP is a noncollagenous extracellular matrix (ECM) protein.
It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains.
Oligomerization results from formation of a five-stranded coiled coil and disulfides.
Binding to other ECM proteins such as collagen appears to depend on divalent cations.
Applications:Suitable for use in ELISA, Western Blot.
Immunohistochemistry and Flow Cytometry (Not Tested).
Other applications have not been tested.
Recommended Dilutions:Immunohistochemistry: Formalin-fixed, paraffin-embedded sectionsOptimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Specificity:Recognizes human COMP.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 314-343 in the central region of human COMP.