84-1675-64　［取扱停止］CLASP2, NT (CLIP-associating Protein 2, Cytoplasmic Linker-associated Protein 2, Protein Orbit Homolog 2, hOrbit2, KIAA0627) (Biotin) 200ul　C5831-03B-Biotin

特徴

• Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules.
• Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell.
• May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2.
• This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling.
• Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
• Applications:Suitable for use in ELISA and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1,000Immunohistochemistry: 1:10-1:50Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.