84-1671-93　［取扱停止］MEK1, phosphorylated (Ser217, Ser221) (MAPK/ERK Kinase 1, MEK 1, Dual Specificity Mitogen-Activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAP2K1, MAPKK 1, MKK1, PRKMK1, ERK Activator Kinase 1) (Biotin) 200ul　M2865-12D-Biotin

特徴

• MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family.
• This kinase is known to play a critical role in mitogen growth factor signal transduction.
• It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3.
• The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases.
• The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
• Applications:Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-1:500Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.