特徴

• Transcriptional corepressor that binds to a number of transcription factors.
• Inhibits NF-kappa-B-regulated gene expression.
• Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling.
• The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
• Unusual function as coactivator for ESRRG.
• Applications:Suitable for use in Western Blot, FLISA
• Recommended Dilution:FLISA: 1:1,000Western Blot: 1:100-500
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: APC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.