This gene encodes a member of the mucin protein family.
Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier.
The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted.
The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades.
The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals.
Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in FLISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry (Not Tested).
Other applications have not been tested.
Recommended Dilution:Immunohistochemistry (Leica): Formalin-fixed, paraffin-embedded sections Requires HIER using EDTA pH 9.0Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: APC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
Specificity：Recognizes human MUC20.
Isotype：IgG
Calc Applications Abbrev：FLISA IF IHC WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 654-684 in the C-terminal region of human MUC20.
