Kr¸ppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon.
It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene.
KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells.
KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.
Applications:Suitable for use in Immunofluorescence, Dot Blot, FLISA
Recommended Dilution:FLISA: 1:1,000Dot Blot 1:50-100
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: APC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：DB FLISA IF
Calc Crossreactivity：Hu
Immunogen：Phospho-KLF4-S245 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 132~161 amino acids surrounding S245 of human KLF4.
