The protein encoded by this gene acts as receptor for arginine vasopressin.
This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors.
Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system.
The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release.
It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome.
A spliced antisense transcript of this gene has been reported but its function is not known.
Applications:Suitable for use in Western Blot and FLISA.
Other applications have not been tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: APC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
Specificity：Recognizes human AVPR1B.
Isotype：IgG
Calc Applications Abbrev：FLISA WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 289-317 in the C-terminal region of human AVPR1B, Swiss/UniProt Accession: P47901
